Question · asked by 1 review

Azelaic acid vs benzoyl peroxide: Participants' global self‐assessment of acne improvement Good or very good improvement (long term: treatment duration > 8 weeks)

Population
participants with acne
Intervention
Azelaic acid
Comparison
benzoyl peroxide
Outcome
Participants' global self‐assessment of acne improvement Good or very good improvement (long term: treatment duration > 8 weeks)

Azelaic acid probably leads to lower participants' global self‐assessment of acne improvement Good or… compared with benzoyl peroxide (moderate certainty).

What each review found

Current versions only
FindingEffectStudiesGRADE certainty
Azelaic acid vs benzoyl peroxide
Participants' global self‐assessment of acne improvement Good or very good improvement (long term: treatment duration > 8 weeks) · participants with acne
Azelaic acid probably leads to lower participants' global self‐assessment of acne improvement Good or… compared with benzoyl peroxide (moderate certainty).
Topical azelaic acid, salicylic acid, nicotinamide, sulphur, zinc and fruit acid (alpha‐hydroxy acid) for acne (2020) · Cochrane Headline outcomes only
RR 0.82 [0.72, 0.95]1 study · 351 participantsModerate

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Topical azelaic acid, salicylic acid, nicotinamide, sulphur, zinc and fruit acid (alpha‐hydroxy acid) for acne
2020 · Cochrane Headline outcomes only
Not reportedNot extractedNot assessed

The same intervention and outcome, asked in another population or against another comparator.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.