Question · asked by 1 review

Resin-based fissure sealant vs Fluoride varnish: Dentine caries in permanent molars (24 months)

Population
Children and adolescents (general population, aged under 20 years)
Intervention
Resin-based fissure sealant
Comparison
Fluoride varnish
Outcome
Dentine caries in permanent molars (24 months)

It is very uncertain whether resin-based fissure sealant changes dentine caries in permanent molars (yes/no) compared with fluoride varnish (very low certainty).

What each review found

Current versions only
No studies found 0 · 0%GRADE not reported 0 · 0%Very low 1 · 50%Low 1 · 50%Moderate 0 · 0%High 0 · 0%
FindingEffectStudiesGRADE certainty
Resin-based fissure sealant vs Fluoride varnish
Dentine caries in permanent molars (yes/no) · Children and adolescents from the general population, younger than 20 years of age at the start of the study · 2-3 years
It is very uncertain whether resin-based fissure sealant changes dentine caries in permanent molars (yes/no) compared with fluoride varnish (very low certainty).
Pit and fissure sealants versus fluoride varnishes for preventing dental decay in the permanent teeth of… (2020) · Cochrane All outcomes
OR 0.67 [0.37, 1.19]4 studies · 1683 participantsVery low
Resin-based fissure sealant vs Fluoride varnish
Dentine caries in permanent molars (yes/no) · Children and adolescents from the general population, younger than 20 years of age at the start of the study · 2 years
Resin-based fissure sealant may leads to lower dentine caries in permanent molars (yes/no) compared with fluoride varnish (low certainty).
Pit and fissure sealants versus fluoride varnishes for preventing dental decay in the permanent teeth of… (2016) · Cochrane All outcomesearlier version CD003067.PUB4, superseded
OR 0.69 [0.50, 0.94]2 studies · 358 participantsLow

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Pit and fissure sealants versus fluoride varnishes for preventing dental decay in the permanent teeth of children and adolescents
2020 · Cochrane All outcomes
19 March 2020Not listedNot assessed
How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.