Question · asked by 1 review
Perioperative beta‐blockers vs placebo or usual care: Hypotension
- Population
- adults undergoing non‐cardiac surgery under general anaesthesia (to include: low‐risk, medium‐risk, and high‐risk surgeries)
- Intervention
- Perioperative beta‐blockers
- Comparison
- placebo or usual care
- Outcome
- Hypotension
Perioperative beta‐blockers probably leads to higher hypotension (within 30 days; as defined by study authors, minimum… compared with placebo or standard care (moderate certainty).
What each review found
Current versions only| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Perioperative beta‐blockers vs placebo or standard care Hypotension (within 30 days; as defined by study authors, minimum systolic blood pressure < 90 mmHg or requiring medication) · adults undergoing non‐cardiac surgery under general anaesthesia (to include: low‐risk, medium‐risk, and high‐risk… Perioperative beta‐blockers probably leads to higher hypotension (within 30 days; as defined by study authors, minimum… compared with placebo or standard care (moderate certainty). Perioperative beta‐blockers for preventing surgery‐related mortality and morbidity in adults undergoing… (2019) · Cochrane Headline outcomes only | RR 1.4 [1.29, 1.51] | 49 studies · 12304 participants | Moderate |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Perioperative beta‐blockers for preventing surgery‐related mortality and morbidity in adults undergoing non‐cardiac surgery 2019 · Cochrane Headline outcomes only | Not reported | Not extracted | Not assessed |
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.