Question · asked by 1 review
Oral midazolam vs A different sedative agent: Behaviour
- Population
- Children and adolescents (0 to 16 years) needing dental treatment
- Intervention
- Oral midazolam
- Comparison
- A different sedative agent
- Outcome
- Behaviour
What each review found
Current versions onlyNo studies found 0 · 0%GRADE not reported 3 · 75%Very low 1 · 25%Low 0 · 0%Moderate 0 · 0%High 0 · 0%
| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Oral midazolam vs A different sedative agent Behaviour · Children and adolescents (0 to 16 years) needing dental treatment Sedation of children undergoing dental treatment (2018) · Cochrane All outcomes | Any behavioural score - Oral midazolam versus (other sedatives): 654 (7); VERY LOW | 7 studies · 654 participants | Very low |
Oral midazolam vs A different sedative agent Behaviour · Children and adolescents (0 to 16 years) needing dental treatment Sedation of children undergoing dental treatment (2012) · Cochrane All outcomesearlier version CD003877.PUB4, superseded | Oral midazolam head-to-head (Baygin 2010; Koirala 2006; Singh 2002): premedication agents better than N2O alone; no significant difference midazolam+N2O vs hydroxyzine or midazolam/ketamine. Narrative. | 3 studies | GRADE not reported |
Oral midazolam vs A different sedative agent Behaviour · Children and adolescents (0 to 16 years) needing dental treatment Sedation of children undergoing dental treatment (2006) · Cochrane All outcomesearlier version CD003877.PUB3, superseded | Oral midazolam head-to-head (Haas 1996; Singh 2002; Musial 2003; Shapira 2004; Myers 2004 submucosal midazolam/CH; Reeves 1996; Dallman 2001): mostly no significant differences; Singh 2002 favoured midazolam. Narrative. | Not reported | GRADE not reported |
Oral midazolam vs A different sedative agent Behaviour · Children and adolescents (0 to 16 years) needing dental treatment Sedation of children undergoing dental treatment (2005) · Cochrane All outcomesearlier version CD003877.PUB2, superseded | Oral midazolam head-to-head: Haas 1996 (vs chloral hydrate); Singh 2002 (vs triclofos/promethazine, midazolam best); Reeves 1996 (midazolam/acetaminophen vs CH/H); Dallman 2001 and Hartgraves 1994 (nasal midazolam vs… | Not reported | GRADE not reported |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Sedation of children undergoing dental treatment 2018 · Cochrane All outcomes | 22 February 2018 | Not listed | Not assessed |
Related questions
The same intervention and outcome, asked in another population or against another comparator.
- Oral midazolam vs placebo or no intervention · Children and adolescents (0 to 16 years) needing dental treatment · 1 review
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.