Question · asked by 1 review

Oral corticosteroids vs placebo or NSAID: Proportion of patients with resolution or improved symptoms at days 3 to 7

Oral corticosteroids probably leads to higher proportion of patients with resolution or improved symptoms at days… compared with placebo or NSAID (moderate certainty).

What each review found

Current versions only
FindingEffectStudiesGRADE certainty
Oral corticosteroids vs placebo or NSAID
Proportion of patients with resolution or improved symptoms at days 3 to 7 · patients with acute sinusitis
Oral corticosteroids probably leads to higher proportion of patients with resolution or improved symptoms at days… compared with placebo or NSAID (moderate certainty).
Systemic corticosteroids for acute sinusitis (2014) · Cochrane Headline outcomes only
RR 1.33 [1.09, 1.62]5 studies · 1043 participantsModerate
Oral corticosteroids vs placebo or NSAID
Proportion of patients with resolution or improved symptoms at days 3 to 7 ‐ Co‐treatment with antibiotics · patients with acute sinusitis
Oral corticosteroids may leads to higher proportion of patients with resolution or improved symptoms at days… compared with placebo or NSAID (low certainty).
Systemic corticosteroids for acute sinusitis (2014) · Cochrane Headline outcomes only
RR 1.4 [1.08, 1.81]4 studies · 869 participantsLow
Oral corticosteroids vs placebo or NSAID
Proportion of patients with resolution or improved symptoms at days 3 to 7 ‐ Corticosteroid monotherapy · patients with acute sinusitis
Oral corticosteroids showed no clear difference in proportion of patients with resolution or improved symptoms at days… compared with placebo or NSAID (moderate certainty).
Systemic corticosteroids for acute sinusitis (2014) · Cochrane Headline outcomes only
RR 1.12 [0.87, 1.44]1 study · 174 participantsModerate

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Systemic corticosteroids for acute sinusitis
2014 · Cochrane Headline outcomes only
Not reportedlist not extracted yetNot assessed

Studies behind the findings

None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.