Question · asked by 1 review

Visual screening (oral visual inspection) by trained health workers vs No screening: Oral cancer mortality (disease-specific)

Population
Apparently healthy adults aged 35 years or older (general population), living in 13 clusters in rural areas of Trivandrum city, Kerala, India
Intervention
Visual screening (oral visual inspection) by trained health workers
Comparison
No screening
Outcome
Oral cancer mortality (disease-specific)

Visual screening (oral visual inspection) by trained health workers showed no clear difference in oral cancer mortality (disease-specific) compared with no screening (low certainty).

What each review found

Current versions only
No studies found 0 · 0%GRADE not reported 6 · 85.7%Very low 0 · 0%Low 1 · 14.3%Moderate 0 · 0%High 0 · 0%
FindingEffectStudiesGRADE certainty
Visual screening (oral visual inspection) by trained health workers vs No screening
Oral cancer mortality (disease-specific) · Apparently healthy adults aged 35 years or older (general population), living in 13 clusters in rural areas of… · 15-year follow-up
Visual screening (oral visual inspection) by trained health workers showed no clear difference in oral cancer mortality (disease-specific) compared with no screening (low certainty).
Screening programmes for the early detection and prevention of oral cancer (2013) · Cochrane All outcomes
RR 0.88 [0.69, 1.12]1 study · 191873 participantsLow
Visual screening (oral visual inspection) by trained health workers vs No screening
Oral cancer mortality (disease-specific) · Apparently healthy adults aged 35 years or older (general population), living in 13 clusters in rural areas of… · 15-year follow-up, High-risk individuals (tobacco and/or alcohol users)
Visual screening (oral visual inspection) by trained health workers led to lower oral cancer mortality (disease-specific) compared with no screening; GRADE not reported.
Screening programmes for the early detection and prevention of oral cancer (2013) · Cochrane All outcomes
RR 0.76 [0.60, 0.97]1 studyGRADE not reported
Visual screening (oral visual inspection) by trained health workers vs No screening
Oral cancer mortality (disease-specific) · Apparently healthy adults aged 35 years or older (general population), living in 13 clusters in rural areas of… · 9-year follow-up
Screening programmes for the early detection and prevention of oral cancer (2010) · Cochrane All outcomesearlier version CD004150.PUB3, superseded
There was no statistically significant difference in the mortality rate for oral cancer between the intervention group and control. Over the 9-year period, 77 of 205 (intervention) and 87 of 158 (control) died;…1 study · 191873 participantsGRADE not reported
Visual screening (oral visual inspection) by trained health workers vs No screening
Oral cancer mortality (disease-specific) · Apparently healthy adults aged 35 years or older (general population), living in 13 clusters in rural areas of… · 9-year follow-up, High-risk individuals (tobacco and/or alcohol users)
Screening programmes for the early detection and prevention of oral cancer (2010) · Cochrane All outcomesearlier version CD004150.PUB3, superseded
For individuals that used tobacco, alcohol or both, a significant reduction of 43% in mortality rates for men (from 42.9 to 24.6 per 100,000 person years). For women, a 22% reduction (from 50.7 to 39.4 per 100,000…1 studyGRADE not reported
Visual screening (oral visual inspection) by trained health workers vs No screening
Oral cancer mortality (disease-specific) · Apparently healthy adults aged 35 years or older (general population), living in 13 clusters in rural areas of… · 9-year follow-up
Screening programmes for the early detection and prevention of oral cancer (2006) · Cochrane All outcomesearlier version CD004150.PUB2, superseded
There was no statistically significant difference in death rate from oral cancer between the intervention group and control. Over the 9-year period, 77 of 205 subjects with oral cancer in the intervention group and 87…1 study · 191873 participantsGRADE not reported
Visual screening (oral visual inspection) by trained health workers vs No screening
Oral cancer mortality (disease-specific) · Apparently healthy adults aged 35 years or older (general population), living in 13 clusters in rural areas of… · 9-year follow-up, High-risk individuals (tobacco and/or alcohol users)
Screening programmes for the early detection and prevention of oral cancer (2006) · Cochrane All outcomesearlier version CD004150.PUB2, superseded
High-risk group (tobacco or alcohol users): deaths 70 (intervention) vs 85 (control); mortality rate 29.9/100,000 person-years vs 45.4/100,000. A significant 34% reduction in mortality was recorded in the high-risk…1 study · 84600 participantsGRADE not reported
Visual screening (oral visual inspection) by trained health workers vs No screening
Oral cancer mortality (disease-specific) · Apparently healthy adults aged 35 years or older (general population), living in 13 clusters in rural areas of… · 6-year follow-up
Screening programmes for the early detection and prevention of oral cancer (2003) · Cochrane All outcomesearlier version CD004150, superseded
There was no statistical significant difference in death rate from oral cancer between the intervention group and control. Over the 6-year period, 65 of 149 subjects with oral cancer in the intervention group and 62 of…1 study · 130779 participantsGRADE not reported

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Screening programmes for the early detection and prevention of oral cancer
2013 · Cochrane All outcomes
22 July 2013Not listedNot assessed
How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.