Question · asked by 1 review
NSAID (systemic) vs paracetamol: Adverse events
- Population
- People undergoing orthodontic treatment (any age; 9 to 34 years in included studies)
- Intervention
- NSAID (systemic)
- Comparison
- paracetamol
- Outcome
- Adverse events
What each review found
Current versions only| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
NSAID (systemic) vs Paracetamol Adverse events · People undergoing orthodontic treatment (any age; 9 to 34 years in included studies) Pharmacological interventions for pain relief during orthodontic treatment (2017) · Cochrane All outcomes | In one study, one participant (<1%) in the paracetamol group experienced drug hypersensitivity (a 'red, blotchy and itchy rash') that resolved without treatment within 1 week (Bradley 2007 / McAlinden 2005); 1 RCT;… | 1 study | Very low |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Pharmacological interventions for pain relief during orthodontic treatment 2017 · Cochrane All outcomes | 2017-06-19 | Not listed | Not assessed |
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.