Early enteral nutrition with supplemental parenteral nutrition (SPN) vs delayed enteral nutrition with SPN: Mortality (timing of outcome measurement unclear)
It is very uncertain whether early enteral nutrition with supplemental parenteral nutrition (SPN) changes mortality (timing of outcome measurement unclear) compared with delayed enteral nutrition with SPN (very low certainty).
What each review found
Current versions only| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Early enteral nutrition with supplemental parenteral nutrition (SPN) vs delayed enteral nutrition with SPN Mortality (timing of outcome measurement unclear) · critically ill adults It is very uncertain whether early enteral nutrition with supplemental parenteral nutrition (SPN) changes mortality (timing of outcome measurement unclear) compared with delayed enteral nutrition with SPN (very low certainty). Early enteral nutrition (within 48 hours) versus delayed enteral nutrition (after 48 hours) with or without… (2019) · Cochrane Headline outcomes only | RR 0.74 [0.25, 2.18] | 1 study · 27 participants | Very low |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Early enteral nutrition (within 48 hours) versus delayed enteral nutrition (after 48 hours) with or without supplemental parenteral… 2019 · Cochrane Headline outcomes only | Not reported | list not extracted yet | Not assessed |
Studies behind the findings
None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.