Question · asked by 1 review

Topical antibiotics with steroids vs topical antibiotics: Resolution of ear discharge ‐ measured at 1 to 2 weeks

Population
people (of any age) with chronic suppurative otitis media or ear discharge
Intervention
Topical antibiotics with steroids
Comparison
topical antibiotics
Outcome
Resolution of ear discharge ‐ measured at 1 to 2 weeks

Topical antibiotics with steroids may leads to lower resolution of ear discharge at between 1 to 2 weeks compared with topical antibiotics alone (low certainty).

What each review found

Current versions only
No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 2 · 100%Moderate 0 · 0%High 0 · 0%
FindingEffectStudiesGRADE certainty
Topical antibiotics with steroids vs topical antibiotics alone
Resolution of ear discharge at between 1 to 2 weeks · people (of any age) with chronic suppurative otitis media or ear discharge
Topical antibiotics with steroids may leads to lower resolution of ear discharge at between 1 to 2 weeks compared with topical antibiotics alone (low certainty).
Topical antibiotics with steroids for chronic suppurative otitis media (2020) · Cochrane Headline outcomes only
RR 0.77 [0.71, 0.84]7 studies · 903 participantsLow
Topical antibiotics with steroids vs topical antibiotics alone (same antibiotics)
Resolution of ear discharge at between 1 to 2 weeks · people (of any age) with chronic suppurative otitis media or ear discharge
Topical antibiotics with steroids showed no clear difference in resolution of ear discharge at between 1 to 2 weeks compared with topical antibiotics alone (same antibiotics) (low certainty).
Topical antibiotics with steroids for chronic suppurative otitis media (2020) · Cochrane Headline outcomes only
RR 1.08 [0.96, 1.21]3 studies · 335 participantsLow

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Topical antibiotics with steroids for chronic suppurative otitis media
2020 · Cochrane Headline outcomes only
Not reportedNot extractedNot assessed

The same intervention and outcome, asked in another population or against another comparator.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.