Question · asked by 1 review

Clotrimazole (partially absorbed from GI tract) vs another azole: Other adverse events

Population
patients with otomycosis
Intervention
Clotrimazole (partially absorbed from GI tract)
Comparison
another azole
Outcome
Other adverse events

It is very uncertain whether clotrimazole changes other adverse events compared with another azole (very low certainty).

What each review found

Include earlier review versions
FindingEffectStudiesGRADE certainty
Clotrimazole vs another azole
Other adverse events · patients with otomycosis
It is very uncertain whether clotrimazole changes other adverse events compared with another azole (very low certainty).
Topical azole treatments for otomycosis (2021) · Cochrane Headline outcomes only
RR 0.79 [0.18, 3.41]1 study · 174 participantsVery low

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Topical azole treatments for otomycosis
2021 · Cochrane Headline outcomes only
Not reportedNot extractedNot assessed
How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.