Concomitant (concurrent) chemoradiotherapy vs chemoradiotherapy plus surgery: Freedom from locoregional relapse
Chemoradiotherapy probably leads to lower freedom from locoregional relapse compared with chemoradiotherapy plus surgery (moderate certainty).
What each review found
Include earlier review versions| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Chemoradiotherapy vs chemoradiotherapy plus surgery Freedom from locoregional relapse · nonmetastatic esophageal cancer Chemoradiotherapy probably leads to lower freedom from locoregional relapse compared with chemoradiotherapy plus surgery (moderate certainty). Chemoradiotherapy versus chemoradiotherapy plus surgery for esophageal cancer (2017) · Cochrane Headline outcomes only | HR 0.55 [0.39, 0.76] | 2 studies · 431 participants | Moderate |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Chemoradiotherapy versus chemoradiotherapy plus surgery for esophageal cancer 2017 · Cochrane Headline outcomes only | Not reported | list not extracted yet | Not assessed |
Studies behind the findings
None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.