Question · asked by 1 review
ARP with allograft plus synthetic cell-binding peptide P-15 vs ARP with allograft without P-15: Complications (e.g. discomfort, pain and swelling)
- Population
- Adults aged 18 years or older, in good general health (including well-controlled systemic disease), requiring extraction of one or more permanent teeth (mandibular or maxillary, molar or non-molar), with consideration of future delayed dental implant placement
- Intervention
- ARP with allograft plus synthetic cell-binding peptide P-15
- Comparison
- ARP with allograft without P-15
- Outcome
- Complications (e.g. discomfort, pain and swelling)
What each review found
Current versions onlyNo studies found 0 · 0%GRADE not reported 1 · 50%Very low 1 · 50%Low 0 · 0%Moderate 0 · 0%High 0 · 0%
| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
ARP with allograft plus synthetic cell-binding peptide P-15 vs ARP with allograft without P-15 Complications (e.g. discomfort, pain and swelling) · Adults aged 18 years or older, in good general health (including well-controlled systemic disease), requiring… · 6 months Interventions for replacing missing teeth: alveolar ridge preservation techniques for dental implant site… (2021) · Cochrane All outcomes | Included study (Fernandes 2011) reported there were no adverse effects | 1 study · 18 participants | Very low |
ARP with allograft plus synthetic cell-binding peptide P-15 vs ARP with allograft without P-15 Complications (e.g. discomfort, pain and swelling) · Adults aged 18 years or older, in good general health (including well-controlled systemic disease), requiring… · At least 6 months (from extraction to final ridge measurement before/at implant placement) Interventions for replacing missing teeth: alveolar ridge preservation techniques for dental implant site… (2015) · Cochrane All outcomesearlier version CD010176.PUB2, superseded | Fernandes 2011 reported the study completed with no postoperative complications; not pooled or GRADE-rated | 1 study | GRADE not reported |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Interventions for replacing missing teeth: alveolar ridge preservation techniques for dental implant site development 2021 · Cochrane All outcomes | 2021-03 | Not listed | Not assessed |
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.