Question · asked by 1 review

Withdrawal of anticholinergic medication vs continuing anticholinergic medication: Leaving the study early

Population
chronic schizophrenia patients with antipsychotic‐induced tardive dyskinesia
Intervention
Withdrawal of anticholinergic medication
Comparison
continuing anticholinergic medication
Outcome
Leaving the study early

It is very uncertain whether withdrawal of anticholinergic medication changes acceptability of the treatment: leaving the study early compared with continuing anticholinergic medication (very low certainty).

What each review found

Include earlier review versions
FindingEffectStudiesGRADE certainty
Withdrawal of anticholinergic medication vs continuing anticholinergic medication
Acceptability of the treatment: leaving the study early · chronic schizophrenia patients with antipsychotic‐induced tardive dyskinesia
It is very uncertain whether withdrawal of anticholinergic medication changes acceptability of the treatment: leaving the study early compared with continuing anticholinergic medication (very low certainty).
Anticholinergic medication for antipsychotic‐induced tardive dyskinesia (2018) · Cochrane Headline outcomes only
RR 2.14 [0.11, 42.52]1 study · 10 participantsVery low

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Anticholinergic medication for antipsychotic‐induced tardive dyskinesia
2018 · Cochrane Headline outcomes only
Not reportedNot extractedNot assessed
How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.