Question · asked by 1 review

HALOPERIDOL vs COMBINATIONS: c. HALOPERIDOL + PROMETHAZINE: Repeated need for tranquillisation ‐ not reported

Population
psychosis‐induced aggression or agitation
Intervention
HALOPERIDOL
Comparison
COMBINATIONS: c. HALOPERIDOL + PROMETHAZINE
Outcome
Repeated need for tranquillisation ‐ not reported

It is very uncertain whether HALOPERIDOL changes repeated need for tranquillisation compared with COMBINATIONS: d. HALOPERIDOL + PROMETHAZINE (very low certainty).

What each review found

Current versions only
FindingEffectStudiesGRADE certainty
HALOPERIDOL vs COMBINATIONS: d. HALOPERIDOL + PROMETHAZINE
Repeated need for tranquillisation · psychosis‐induced aggression or agitation
It is very uncertain whether HALOPERIDOL changes repeated need for tranquillisation compared with COMBINATIONS: d. HALOPERIDOL + PROMETHAZINE (very low certainty).
Haloperidol for psychosis‐induced aggression or agitation (rapid tranquillisation) (2017) · Cochrane Headline outcomes only
RR 0.78 [0.43, 1.41]2 studies · 376 participantsVery low

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Haloperidol for psychosis‐induced aggression or agitation (rapid tranquillisation)
2017 · Cochrane Headline outcomes only
Not reportedNot extractedNot assessed

The same intervention and outcome, asked in another population or against another comparator.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.