Nicotine EC vs non‐nicotine EC: Smoking cessation
Nicotine EC probably leads to higher smoking cessation at 6‐12 months compared with non‐nicotine EC (moderate certainty).
What each review found
Current versions only| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Nicotine EC vs non‐nicotine EC Smoking cessation at 6‐12 months · People who smoke cigarettes Nicotine EC probably leads to higher smoking cessation at 6‐12 months compared with non‐nicotine EC (moderate certainty). Electronic cigarettes for smoking cessation (2024) · Cochrane Headline outcomes only | RR 1.46 [1.09, 1.96] | 6 studies · 1613 participants | Moderate |
Nicotine EC vs non‐nicotine EC Smoking cessation at 6‐12 months · People who smoke cigarettes Nicotine EC probably leads to higher smoking cessation at 6‐12 months compared with non‐nicotine EC (moderate certainty). Electronic cigarettes for smoking cessation (2022) · Cochrane Headline outcomes onlyearlier version CD010216.PUB7, superseded | RR 1.94 [1.21, 3.13] | 5 studies · 1447 participants | Moderate |
Nicotine EC vs non‐nicotine EC Smoking cessation at 6‐12 months · People who smoke cigarettes Nicotine EC probably leads to higher smoking cessation at 6‐12 months compared with non‐nicotine EC (moderate certainty). Electronic cigarettes for smoking cessation (2021) · Cochrane Headline outcomes onlyearlier version CD010216.PUB5, superseded | RR 1.7 [1.03, 2.81] | 4 studies · 1057 participants | Moderate |
Nicotine EC vs non‐nicotine EC Smoking cessation at 6‐12 months · People who smoke cigarettes Nicotine EC showed no clear difference in smoking cessation at 6‐12 months compared with non‐nicotine EC (moderate certainty). Electronic cigarettes for smoking cessation (2020) · Cochrane Headline outcomes onlyearlier version CD010216.PUB4, superseded | RR 1.71 [1, 2.92] | 3 studies · 802 participants | Moderate |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Electronic cigarettes for smoking cessation 2024 · Cochrane Headline outcomes only | Not reported | list not extracted yet | Not assessed |
Studies behind the findings
None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.