Question · asked by 1 review

Methylphenidate vs placebo: Change in apathy

What each review found

Current versions only
FindingEffectStudiesGRADE certainty
Methylphenidate vs placebo
Change in apathy (AES score) · Apathy in people with mild‐to‐moderate Alzheimer's disease
Pharmacological interventions for apathy in Alzheimer's disease (2018) · Cochrane Headline outcomes only
no estimate extracted3 studies · 145 participantsLow
Methylphenidate vs placebo
Change in apathy (NPI‐apathy subscale score) · Apathy in people with mild‐to‐moderate Alzheimer's disease
Pharmacological interventions for apathy in Alzheimer's disease (2018) · Cochrane Headline outcomes only
no estimate extracted2 studies · 85 participantsLow

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Pharmacological interventions for apathy in Alzheimer's disease
2018 · Cochrane Headline outcomes only
Not reportedlist not extracted yetNot assessed

Studies behind the findings

None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.