Question · asked by 1 review

AD26.COV2.S – Janssen Pharmaceutical Companies vs placebo: All‐cause mortalityb

AD26.COV2.S – Janssen Pharmaceutical Companies leads to lower all‐cause mortalityb compared with placebo (high certainty).

What each review found

Current versions only
FindingEffectStudiesGRADE certainty
AD26.COV2.S – Janssen Pharmaceutical Companies vs placebo
All‐cause mortalityb
AD26.COV2.S – Janssen Pharmaceutical Companies leads to lower all‐cause mortalityb compared with placebo (high certainty).
Efficacy and safety of COVID‐19 vaccines (2022) · Cochrane Headline outcomes only
RR 0.25 [0.09, 0.67]1 study · 43783 participantsHigh

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Efficacy and safety of COVID‐19 vaccines
2022 · Cochrane Headline outcomes only
Not reportedlist not extracted yetNot assessed

Studies behind the findings

None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.