Question · asked by 1 review

Donepezil 23 mg/day vs donepezil 10 mg/day: Change in capacity for activities of daily living

What each review found

Current versions only
FindingEffectStudiesGRADE certainty
Donepezil 23 mg/day vs donepezil 10 mg/day
Activities of daily living (change from baseline at 24 weeks using the ADCS‐ADL‐sev) · people with Alzheimer's disease
Donepezil for dementia due to Alzheimer's disease (2018) · Cochrane Headline outcomes only
no estimate extracted1 study · 1396 participantsModerate

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Donepezil for dementia due to Alzheimer's disease
2018 · Cochrane Headline outcomes only
Not reportedlist not extracted yetNot assessed

Studies behind the findings

None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.