VGB vs CBZ monotherapy: Time to achieve 6‐month remission after the first 6 weeks of dose stabilisation from randomisation
It is very uncertain whether VGB changes time to achieve 6‐month remission after the first 6 weeks of dose… compared with CBZ monotherapy (very low certainty).
What each review found
Current versions only| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
VGB vs CBZ monotherapy Time to achieve 6‐month remission after the first 6 weeks of dose stabilisation from randomisation · patients with epilepsy It is very uncertain whether VGB changes time to achieve 6‐month remission after the first 6 weeks of dose… compared with CBZ monotherapy (very low certainty). Vigabatrin versus carbamazepine monotherapy for epilepsy (2015) · Cochrane Headline outcomes only | HR 1.18 [0.89, 1.55] | 1 study · 404 participants | Very low |
VGB vs CBZ monotherapy Time to achieve six‐month remission after the first 6 weeks dose stabilisation from randomisation · Patients with epilepsy It is very uncertain whether VGB changes time to achieve six‐month remission after the first 6 weeks dose… compared with CBZ monotherapy (very low certainty). Vigabatrin versus carbamazepine monotherapy for epilepsy (2012) · Cochrane Headline outcomes onlyearlier version CD008781.PUB2, superseded | HR 1.18 [0.89, 1.55] | 1 study · 404 participants | Very low |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Vigabatrin versus carbamazepine monotherapy for epilepsy 2015 · Cochrane Headline outcomes only | Not reported | list not extracted yet | Not assessed |
Studies behind the findings
None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.