Question · asked by 0 reviews

Radiotherapy vs control: Progression to visual loss (loss of 3 or more lines on logMAR chart)

Radiotherapy showed no clear difference in three or more lines visual acuity lost compared with control (moderate certainty).

What each review found

Current versions only
FindingEffectStudiesGRADE certainty
Radiotherapy vs control
Three or more lines visual acuity lost · patients with neovascular age‐related macular degeneration
Radiotherapy showed no clear difference in three or more lines visual acuity lost compared with control (moderate certainty).
Radiotherapy for neovascular age‐related macular degeneration (2010) · Cochrane Headline outcomes onlyearlier version CD004004.PUB3, superseded
RR 0.9 [0.74, 1.1]8 studies · 759 participantsModerate
Radiotherapy vs control
Three or more lines visual acuity lost · patients with neovascular age‐related macular degeneration
Radiotherapy showed no clear difference in three or more lines visual acuity lost compared with control (low certainty).
Radiotherapy for neovascular age‐related macular degeneration (2010) · Cochrane Headline outcomes onlyearlier version CD004004.PUB3, superseded
RR 0.81 [0.63, 1.03]4 studies · 428 participantsLow

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Radiotherapy for neovascular age‐related macular degeneration
2020 · Cochrane Headline outcomes only
Not reportedlist not extracted yetNot assessed

Studies behind the findings

None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.