Question · asked by 1 review

Full-mouth disinfection (FMD): scaling/root planing (subgingival instrumentation) of all quadrants within 24 hours plus adjunctive antiseptic (chlorhexidine) treatments (rinsing, pocket irrigation, tongue/tonsil brushing) vs Quadrant scaling and root planing (control): SRP of each quadrant in separate sessions at least one week apart: Adverse events

Population
Adults with a clinical diagnosis of (chronic) periodontitis (1999 classification); studies of aggressive periodontitis, systemic disorders or antibiotic use excluded
Intervention
Full-mouth disinfection (FMD): scaling/root planing (subgingival instrumentation) of all quadrants within 24 hours plus adjunctive antiseptic (chlorhexidine) treatments (rinsing, pocket irrigation, tongue/tonsil brushing)
Comparison
Quadrant scaling and root planing (control): SRP of each quadrant in separate sessions at least one week apart
Outcome
Adverse events

What each review found

Current versions only
No studies found 0 · 0%GRADE not reported 2 · 100%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%
FindingEffectStudiesGRADE certainty
Full-mouth disinfection (FMD): scaling/root planing (subgingival instrumentation) of all quadrants within 24 hours plus adjunctive antiseptic (chlorhexidine) treatments (rinsing, pocket irrigation, tongue/tonsil brushing) vs Quadrant scaling and root planing (control): SRP of each quadrant in separate sessions at least one week apart
Adverse events · Adults with a clinical diagnosis of (chronic) periodontitis (1999 classification); studies of aggressive…
Full‐mouth treatment modalities (within 24 hours) for periodontitis in adults (2022) · Cochrane All outcomes
13 studies provided adverse-event/participant-reported information; 3 reported an event after FMD or FMS; most important harm was increased body temperature. FMD/chlorhexidine-specific harms reported by Fonseca 2015…13 studiesGRADE not reported
Full-mouth disinfection (FMD): scaling/root planing (subgingival instrumentation) of all quadrants within 24 hours plus adjunctive antiseptic (chlorhexidine) treatments (rinsing, pocket irrigation, tongue/tonsil brushing) vs Quadrant scaling and root planing (control): SRP of each quadrant in separate sessions at least one week apart
Adverse events · Adults with a clinical diagnosis of chronic periodontitis; studies of aggressive periodontitis, systemic disorders or…
Full‐mouth treatment modalities (within 24 hours) for periodontitis in adults (2015) · Cochrane All outcomesearlier version CD004622.PUB3, superseded
Adverse events reported in 8 studies; most important harm was an increased body temperature after FMS or FMD treatments; narrative, not separated by comparison and not GRADE-rated.8 studiesGRADE not reported

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Full‐mouth treatment modalities (within 24 hours) for periodontitis in adults
2022 · Cochrane All outcomes
2021-06Not listedNot assessed

The same intervention and outcome, asked in another population or against another comparator.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.