Question · asked by 1 review

Benzoyl peroxide vs salicylic acid: Adverse effect/event: 2. Adverse effects ‐ any ‐ medium‐termonly

Population
participants with acne
Intervention
Benzoyl peroxide
Comparison
salicylic acid
Outcome
Adverse effect/event: 2. Adverse effects ‐ any ‐ medium‐termonly

It is very uncertain whether benzoyl peroxide changes total number of participants with any adverse events (medium‐term… compared with salicylic acid (very low certainty).

What each review found

Current versions only
FindingEffectStudiesGRADE certainty
Benzoyl peroxide vs salicylic acid
Total number of participants with any adverse events (medium‐term data) Treatment duration: 6 weeks · acne vulgaris
It is very uncertain whether benzoyl peroxide changes total number of participants with any adverse events (medium‐term… compared with salicylic acid (very low certainty).
Topical benzoyl peroxide for acne (2020) · Cochrane Headline outcomes only
RR 4.77 [0.24, 93.67]1 study · 41 participantsVery low

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Topical benzoyl peroxide for acne
2020 · Cochrane Headline outcomes only
Not reportedNot extractedNot assessed
How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.