Question · asked by 1 review

Pre‐mixed insulin (70 NPH/30 REG) vs self‐mixed split dose insulin (Different insulin regimens with similar insulin types used within the regimen): Caesarean section 4

Population
pregnant women with pre‐existing diabetes
Intervention
Pre‐mixed insulin (70 NPH/30 REG)
Comparison
self‐mixed split dose insulin (Different insulin regimens with similar insulin types used within the regimen)
Outcome
Caesarean section 4

It is very uncertain whether pre‐mixed insulin (70 NPH/30 REG) changes caesarean section 4 compared with self‐mixed split dose insulin (Different insulin regimens with… (very low certainty).

What each review found

Current versions only
FindingEffectStudiesGRADE certainty
Pre‐mixed insulin (70 NPH/30 REG) vs self‐mixed split dose insulin (Different insulin regimens with similar insulin types used within the regimen)
Caesarean section 4 · pregnant women with pre‐existing diabetes
It is very uncertain whether pre‐mixed insulin (70 NPH/30 REG) changes caesarean section 4 compared with self‐mixed split dose insulin (Different insulin regimens with… (very low certainty).
Different insulin types and regimens for pregnant women with pre‐existing diabetes (2017) · Cochrane Headline outcomes only
RR 0.57 [0.25, 1.32]1 study · 93 participantsVery low

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Different insulin types and regimens for pregnant women with pre‐existing diabetes
2017 · Cochrane Headline outcomes only
Not reportedNot extractedNot assessed
How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.