Question · asked by 1 review

Topotecon+Carboplatin+Paclitaxel vs Carboplatin+Paclitaxel: Progression‐free survival

Topotecon+Carboplatin+Paclitaxel may leads to higher progress free survival compared with carboplatin+Paclitaxel (low certainty).

What each review found

Current versions only
FindingEffectStudiesGRADE certainty
Topotecon+Carboplatin+Paclitaxel vs Carboplatin+Paclitaxel
Progress free survival · patients with ovarian cancer
Topotecon+Carboplatin+Paclitaxel may leads to higher progress free survival compared with carboplatin+Paclitaxel (low certainty).
Topotecan for ovarian cancer (2008) · Cochrane Headline outcomes only
HR 1.03 [1.03, 1.03]2 studies · 1998 participantsLow

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Topotecan for ovarian cancer
2008 · Cochrane Headline outcomes only
Not reportedlist not extracted yetNot assessed

Studies behind the findings

None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.