Question · asked by 1 review

Active topical agent vs placebo or control: Proportion of participants developing a new pressure ulcer

It is very uncertain whether active topical agent changes pressure ulcer incidence: active lotion vs placebo compared with placebo/control (very low certainty).

What each review found

Current versions only
FindingEffectStudiesGRADE certainty
Active topical agent vs placebo/control
Pressure ulcer incidence: active lotion vs placebo · individuals at risk of pressure ulcer development
It is very uncertain whether active topical agent changes pressure ulcer incidence: active lotion vs placebo compared with placebo/control (very low certainty).
Dressings and topical agents for preventing pressure ulcers (2018) · Cochrane Headline outcomes only
RR 0.73 [0.45, 1.19]1 study · 167 participantsVery low
Active topical agent vs placebo/control
Pressure ulcer incidence: DMSO cream vs placebo · individuals at risk of pressure ulcer development
Active topical agent may leads to higher pressure ulcer incidence: DMSO cream vs placebo compared with placebo/control (low certainty).
Dressings and topical agents for preventing pressure ulcers (2018) · Cochrane Headline outcomes only
RR 1.99 [1.1, 3.57]1 study · 61 participantsLow

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Dressings and topical agents for preventing pressure ulcers
2018 · Cochrane Headline outcomes only
Not reportedlist not extracted yetNot assessed

Studies behind the findings

None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.