Question · asked by 1 review
Xylitol syrup (high dose, 8 g/day) vs Control (low-dose xylitol, 2.67 g/day) syrup: Adverse effects (loose stools, diarrhoea)
- Population
- Infants (primary teeth; baseline about 9 to 15 months)
- Intervention
- Xylitol syrup (high dose, 8 g/day)
- Comparison
- Control (low-dose xylitol, 2.67 g/day) syrup
- Outcome
- Adverse effects (loose stools, diarrhoea)
What each review found
Current versions only| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Xylitol syrup (high dose, 8 g/day) vs Control (low-dose xylitol, 2.67 g/day) syrup Adverse effects (loose stools, diarrhoea) · Infants (primary teeth; baseline about 9 to 15 months) · 12 months Xylitol‐containing products for preventing dental caries in children and adults (2015) · Cochrane All outcomes | Adverse effects were not reported in a usable format, but the reported rates of loose stools and diarrhoea were very similar between groups. There were no serious adverse effects during the study. Milgrom 2009. | 1 study · 94 participants | GRADE not reported |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Xylitol‐containing products for preventing dental caries in children and adults 2015 · Cochrane All outcomes | 2014-08 | Not listed | Not assessed |
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.