Question · asked by 1 review

Summary of findings ‐ 400 mg inhaled mannitol vs 50 mg inhaled mannitol: Adverse events relating to treatment Scale: mild, moderate, severe and total

Population
adults, children and young people with CF
Intervention
Summary of findings ‐ 400 mg inhaled mannitol
Comparison
50 mg inhaled mannitol
Outcome
Adverse events relating to treatment Scale: mild, moderate, severe and total

What each review found

Current versions only
No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 2 · 100%High 0 · 0%
FindingEffectStudiesGRADE certainty
Summary of findings ‐ 400 mg inhaled mannitol vs 50 mg inhaled mannitol
Adverse events relating to treatment Scale: mild, moderate, severe and total · adults, children and young people with CF
Inhaled mannitol for cystic fibrosis (2020) · Cochrane Headline outcomes only
no estimate extracted2 studies · 600 participantsModerate
Summary of findings ‐ 400 mg inhaled mannitol vs 50 mg inhaled mannitol
Adverse events relating to treatment Scale: mild, moderate, severe and total · adults, children and young people with CF
Inhaled mannitol for cystic fibrosis (2018) · Cochrane Headline outcomes onlyearlier version CD008649.PUB3, superseded
no estimate extracted2 studies · 600 participantsModerate

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Inhaled mannitol for cystic fibrosis
2020 · Cochrane Headline outcomes only
Not reportedNot extractedNot assessed

The same intervention and outcome, asked in another population or against another comparator.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.