Fluoroquinolones vs beta‐lactams: Discontinuation of medication due to adverse events
It is very uncertain whether fluoroquinolones changes adverse events leading to discontinuation of treatment compared with beta‐lactams (very low certainty).
What each review found
Current versions only| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Fluoroquinolones vs beta‐lactams Adverse events leading to discontinuation of treatment · patients with Shigella dysentery It is very uncertain whether fluoroquinolones changes adverse events leading to discontinuation of treatment compared with beta‐lactams (very low certainty). Antibiotic therapy for Shigella dysentery (2010) · Cochrane Headline outcomes onlyearlier version CD006784.PUB3, superseded | RR 1.02 [0.27, 3.89] | 1 study · 127 participants | Very low |
Fluoroquinolones vs beta‐lactams Adverse events leading to discontinuation of treatment · patients with Shigella dysentery It is very uncertain whether fluoroquinolones changes adverse events leading to discontinuation of treatment compared with beta‐lactams (very low certainty). Antibiotic therapy for Shigella dysentery (2010) · Cochrane Headline outcomes only | RR 1.02 [0.27, 3.89] | 1 study · 127 participants | Very low |
Fluoroquinolones vs beta‐lactams Adverse events leading to discontinuation of treatment · patients with Shigella dysentery It is very uncertain whether fluoroquinolones changes adverse events leading to discontinuation of treatment compared with beta‐lactams (very low certainty). Antibiotic therapy for Shigella dysentery (2009) · Cochrane Headline outcomes onlyearlier version CD006784.PUB2, superseded | RR 1.02 [0.27, 3.89] | 1 study · 127 participants | Very low |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Antibiotic therapy for Shigella dysentery 2010 · Cochrane Headline outcomes only | Not reported | list not extracted yet | Not assessed |
Studies behind the findings
None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.