Question · asked by 1 review

STANDARD LOWER DOSE (> 3 to 7.5 mg/day) vs OTHER DOSES: Specific behaviour ‐ agitation

It is very uncertain whether STANDARD LOWER DOSE (> 3 to 7.5 mg/day) changes mental state/behaviour: clinically significant agitation (2‐10 weeks) compared with OTHER DOSES (very low certainty).

What each review found

Current versions only
FindingEffectStudiesGRADE certainty
STANDARD LOWER DOSE (> 3 to 7.5 mg/day) vs OTHER DOSES
Mental state/behaviour: clinically significant agitation (2‐10 weeks) · people with the acute phase of schizophrenia
It is very uncertain whether STANDARD LOWER DOSE (> 3 to 7.5 mg/day) changes mental state/behaviour: clinically significant agitation (2‐10 weeks) compared with OTHER DOSES (very low certainty).
Haloperidol dose for the acute phase of schizophrenia (2013) · Cochrane Headline outcomes only
RR 0.93 [0.69, 1.26]1 study · 65 participantsVery low

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Haloperidol dose for the acute phase of schizophrenia
2013 · Cochrane Headline outcomes only
Not reportedlist not extracted yetNot assessed

Studies behind the findings

None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.