Alemtuzumab 12 mg vs interferon beta‐1a: Number of participants with new or enlarging T2‐hyperintense lesions on MRI
Alemtuzumab 12 mg probably leads to lower number of participants with new or enlarging T2‐hyperintense lesions compared with interferon beta‐1a (moderate certainty).
What each review found
Current versions only| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Alemtuzumab 12 mg vs interferon beta‐1a Number of participants with new or enlarging T2‐hyperintense lesions · patients with multiple sclerosis Alemtuzumab 12 mg probably leads to lower number of participants with new or enlarging T2‐hyperintense lesions compared with interferon beta‐1a (moderate certainty). Alemtuzumab for multiple sclerosis (2016) · Cochrane Headline outcomes onlyearlier version CD011203.PUB2, superseded | RR 0.74 [0.59, 0.91] | 2 studies · 1238 participants | Moderate |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Alemtuzumab for multiple sclerosis 2023 · Cochrane Headline outcomes only | Not reported | list not extracted yet | Not assessed |
Studies behind the findings
None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.