Question · asked by 1 review

Macrolides vs placebo: Use of rescue medication

What each review found

Current versions only
FindingEffectStudiesGRADE certainty
Macrolides vs placebo
Rescue medication (puffs/day) Weighted mean study duration: 17 weeks · adults and children with chronic asthma
Macrolides versus placebo for chronic asthma (2021) · Cochrane Headline outcomes only
no estimate extracted4 studies · 314 participantsLow
Macrolide vs placebo
Rescue medication, puffs/day 17 weeks · adults and children with chronic asthma
Macrolides versus placebo for chronic asthma (2015) · Cochrane Headline outcomes onlyearlier version CD002997.PUB4, superseded
no estimate extracted4 studies · 314 participantsVery low

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Macrolides versus placebo for chronic asthma
2021 · Cochrane Headline outcomes only
Not reportedlist not extracted yetNot assessed

Studies behind the findings

None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.