Question · asked by 1 review

Topical treatments (topical urea 10%) vs placebo: Relief of burning/discomfort (symptom relief; pain intensity)

Population
People with primary burning mouth syndrome (BMS), that is, oral mucosal pain with no dental or medical cause for such symptoms
Intervention
Topical treatments (topical urea 10%)
Comparison
placebo
Outcome
Relief of burning/discomfort (symptom relief; pain intensity)

What each review found

Current versions only
FindingEffectStudiesGRADE certainty
Topical treatments (topical urea 10%) vs Placebo
Relief of burning/discomfort (symptom relief; pain intensity) · People with primary burning mouth syndrome (BMS), that is, oral mucosal pain with no dental or medical cause for such… · short-term (up to 3 months), topical urea 10%
Interventions for treating burning mouth syndrome (2016) · Cochrane All outcomes
Topical urea 10% (Alvarenga da Silva 2014) contributes to the topical treatments short-term symptom-relief comparison (insufficient/contradictory); no separate estimate reported.1 study · 38 participantsGRADE not reported

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Interventions for treating burning mouth syndrome
2016 · Cochrane All outcomes
2015-12Not listedNot assessed
How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.