Question · asked by 1 review
Cleft lip and/or palate (CL/P) vs Healthy controls without cleft: Clinical attachment level (CAL)
- Population
- Individuals assessed for periodontal health (mainly children and adolescents, age >2 years)
- Intervention
- Cleft lip and/or palate (CL/P)
- Comparison
- Healthy controls without cleft
- Outcome
- Clinical attachment level (CAL)
Clinical attachment level loss is greater in persons with orofacial cleft than in healthy controls (p<0.00001), but no pooled effect size was reported (ungraded).
What each review found
Current versions only| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Orofacial cleft (cleft lip and/or palate) as exposure vs Healthy controls without cleft Clinical Attachment Level (CAL) · Individuals assessed for periodontal health (mainly children and adolescents, age >2 years) · Clinical dental examination; various countries (e.g., Brazil, India, China, Thailand, USA) Clinical attachment level loss is greater in persons with orofacial cleft than in healthy controls (p<0.00001), but no pooled effect size was reported (ungraded). Oral health in patients with cleft lip and palate: a systematic literature review and meta-analysis of… (2025) All outcomes | The loss of clinical attachment level (CAL) is greater in patients with cleft lip and palate than in healthy controls (p < 0.00001) | Not reported | GRADE not reported |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Oral health in patients with cleft lip and palate: a systematic literature review and meta-analysis of periodontal and dental disease and… 2025 All outcomes | March 2023 to January 2024 | 30 | Not applicable |
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.