Question · asked by 1 review

Intralesional triamcinolone vs Intralesional salvianolic acid B: Maximal mouth opening (interincisal distance)

Population
People of any age with a confirmed diagnosis, by clinical examination and biopsy, of oral submucous fibrosis (OSF)
Intervention
Intralesional triamcinolone
Comparison
Intralesional salvianolic acid B
Outcome
Maximal mouth opening (interincisal distance)

It is very uncertain whether intralesional triamcinolone changes maximal mouth opening (interincisal distance) compared with intralesional salvianolic acid B (very low certainty).

What each review found

Current versions only
FindingEffectStudiesGRADE certainty
Intralesional triamcinolone vs Intralesional salvianolic acid B
Maximal mouth opening (interincisal distance) · People of any age with a confirmed diagnosis, by clinical examination and biopsy, of oral submucous fibrosis (OSF) · More than 6 months
It is very uncertain whether intralesional triamcinolone changes maximal mouth opening (interincisal distance) compared with intralesional salvianolic acid B (very low certainty).
Interventions for managing oral submucous fibrosis (2024) · Cochrane All outcomes
MD -0.60 [-3.76, 2.56]1 study · 28 participantsVery low

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Interventions for managing oral submucous fibrosis
2024 · Cochrane All outcomes
2022-09Not listedNot assessed

The same intervention and outcome, asked in another population or against another comparator.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.