Sarilumab vs usual care: All‐cause mortality D60 or more
Sarilumab showed no clear difference in all‐cause mortality D60 or above compared with standard care (low certainty).
What each review found
Current versions only| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Sarilumab vs standard care All‐cause mortality D60 or above · participants with severe/critical COVID‐19 Sarilumab showed no clear difference in all‐cause mortality D60 or above compared with standard care (low certainty). Interleukin‐6 blocking agents for treating COVID‐19: a living systematic review (2021) · Cochrane Headline outcomes onlyearlier version CD013881, superseded | RR 1 [0.5, 2] | 1 study · 420 participants | Low |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Interleukin‐6 blocking agents for treating COVID‐19: a living systematic review 2023 · Cochrane Headline outcomes only | Not reported | list not extracted yet | Not assessed |
Studies behind the findings
None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.