Question · asked by 1 review

Taxane followed by anthracyclines vs anthracyclines followed by taxane: Treatment adherence (defined as dose delay) (

Taxane followed by anthracyclines showed no clear difference in treatment adherence (defined as dose delay) ( compared with anthracyclines followed by taxane (moderate certainty).

What each review found

Current versions only
FindingEffectStudiesGRADE certainty
Taxane followed by anthracyclines vs anthracyclines followed by taxane
Treatment adherence (defined as dose delay) ( · adjuvant therapy for early breast cancer
Taxane followed by anthracyclines showed no clear difference in treatment adherence (defined as dose delay) ( compared with anthracyclines followed by taxane (moderate certainty).
Sequencing of anthracyclines and taxanes in neoadjuvant and adjuvant therapy for early breast cancer (2019) · Cochrane Headline outcomes only
RR 0.76 [0.52, 1.12]3 studies · 238 participantsModerate

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Sequencing of anthracyclines and taxanes in neoadjuvant and adjuvant therapy for early breast cancer
2019 · Cochrane Headline outcomes only
Not reportedlist not extracted yetNot assessed

Studies behind the findings

None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.