Question · asked by 1 review

Oral etoposide vs ABV: All‐cause mortality

Population
HIV‐infected adults with severe (T1) Kaposi's sarcoma
Intervention
Oral etoposide
Comparison
ABV
Outcome
All‐cause mortality

Oral etoposide showed no clear difference in mortality compared with ABV (moderate certainty).

What each review found

Include earlier review versions
FindingEffectStudiesGRADE certainty
Oral etoposide vs ABV
Mortality · HIV‐infected adults with severe (T1) Kaposi's sarcoma
Oral etoposide showed no clear difference in mortality compared with ABV (moderate certainty).
Treatment of severe or progressive Kaposi's sarcoma in HIV‐infected adults (2014) · Cochrane Headline outcomes only
RR 1.08 [0.98, 1.19]1 study · 178 participantsModerate

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Treatment of severe or progressive Kaposi's sarcoma in HIV‐infected adults
2014 · Cochrane Headline outcomes only
Not reportedNot extractedNot assessed
How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.