Question · asked by 1 review

Oestrogen cream vs other regimens: Improvement in symptoms (participant‐assessed) oestrogen cream vs placebo)

Oestrogen cream may leads to higher improvement in symptoms (participant‐assessed) oestrogen cream vs… compared with other regimens (low certainty).

What each review found

Current versions only
FindingEffectStudiesGRADE certainty
Oestrogen cream vs other regimens
Improvement in symptoms (participant‐assessed) oestrogen cream vs placebo) · postmenopausal women with vaginal atrophy
Oestrogen cream may leads to higher improvement in symptoms (participant‐assessed) oestrogen cream vs… compared with other regimens (low certainty).
Local oestrogen for vaginal atrophy in postmenopausal women (2016) · Cochrane Headline outcomes only
OR 4.1 [1.88, 8.93]2 studies · 198 participantsLow

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Local oestrogen for vaginal atrophy in postmenopausal women
2016 · Cochrane Headline outcomes only
Not reportedlist not extracted yetNot assessed

Studies behind the findings

None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.