Adjunctive local antibiotic (8.5% doxycycline hyclate, Atridox) added to manual debridement vs Manual debridement plus chlorhexidine irrigation/gel: Change in probing attachment level (PAL)
Adjunctive local antibiotic (8.5% doxycycline hyclate, Atridox)… led to higher change in probing attachment level (PAL) compared with manual debridement with chlorhexidine (no antibiotic); GRADE not reported.
What each review found
Current versions only| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Adjunctive local antibiotic (8.5% doxycycline hyclate, Atridox) added to manual debridement vs Manual debridement with chlorhexidine (no antibiotic) Change in probing attachment level (PAL) · People with at least one dental implant affected by peri-implantitis · 4 months (18 weeks) Adjunctive local antibiotic (8.5% doxycycline hyclate, Atridox)… led to higher change in probing attachment level (PAL) compared with manual debridement with chlorhexidine (no antibiotic); GRADE not reported. Interventions for replacing missing teeth: treatment of peri‐implantitis (2012) · Cochrane All outcomes | MD 0.61 [0.40, 0.82] | 1 study · 28 participants | GRADE not reported |
Adjunctive local antibiotic (8.5% doxycycline hyclate, Atridox) added to manual debridement vs Manual debridement with chlorhexidine (no antibiotic) Change in probing attachment level (PAL) · People with at least one dental implant affected by perimplantitis · 4 months (18 weeks) Adjunctive local antibiotic (8.5% doxycycline hyclate, Atridox)… led to higher change in probing attachment level (PAL) compared with manual debridement with chlorhexidine (no antibiotic); GRADE not reported. Interventions for replacing missing teeth: treatment of peri‐implantitis (2010) · Cochrane All outcomesearlier version CD004970.PUB4, superseded | MD 0.61 [0.40, 0.82] | 1 study · 28 participants | GRADE not reported |
Adjunctive local antibiotic (8.5% doxycycline hyclate, Atridox) added to manual debridement vs Manual debridement with chlorhexidine (no antibiotic) Change in probing attachment level (PAL) · People with at least one dental implant affected by perimplantitis · 4 months (18 weeks) Adjunctive local antibiotic (8.5% doxycycline hyclate, Atridox)… led to higher change in probing attachment level (PAL) compared with manual debridement with chlorhexidine (no antibiotic); GRADE not reported. Interventions for replacing missing teeth: treatment of peri‐implantitis (2008) · Cochrane All outcomesearlier version CD004970.PUB3, superseded | MD 0.61 [0.40, 0.82] | 1 study · 28 participants | GRADE not reported |
Adjunctive local antibiotic (8.5% doxycycline hyclate, Atridox) added to manual debridement vs Manual debridement with chlorhexidine (no antibiotic) Change in probing attachment level (PAL) · People with at least one dental implant affected by perimplantitis · 4 months (18 weeks) Adjunctive local antibiotic (8.5% doxycycline hyclate, Atridox)… led to higher change in probing attachment level (PAL) compared with manual debridement with chlorhexidine (no antibiotic); GRADE not reported. Interventions for replacing missing teeth: treatment of peri‐implantitis (2006) · Cochrane All outcomesearlier version CD004970.PUB2, superseded | MD 0.61 [0.40, 0.82] | 1 study · 28 participants | GRADE not reported |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Interventions for replacing missing teeth: treatment of peri‐implantitis 2012 · Cochrane All outcomes | 2011-06 | list not extracted yet | Not assessed |
Studies behind the findings
None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.