Question · asked by 1 review

Keratinocyte growth factor (KGF), higher dose/regimen vs Keratinocyte growth factor (KGF), different (lower) dose/regimen: Oral mucositis (any severity)

Population
Adults with cancer receiving treatment
Intervention
Keratinocyte growth factor (KGF), higher dose/regimen
Comparison
Keratinocyte growth factor (KGF), different (lower) dose/regimen
Outcome
Oral mucositis (any severity)

What each review found

Current versions only
FindingEffectStudiesGRADE certainty
Keratinocyte growth factor (KGF), higher dose/regimen vs Keratinocyte growth factor (KGF), different (lower) dose/regimen
Oral mucositis (any severity) · Adults with cancer receiving treatment
Interventions for preventing oral mucositis in patients with cancer receiving treatment: cytokines and… (2017) · Cochrane All outcomes
Some inconsistent evidence from which no conclusions can be drawn regarding different dosages of KGF (Analyses 2.1 to 2.8); no pooled estimate reportedNot reportedGRADE not reported

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Interventions for preventing oral mucositis in patients with cancer receiving treatment: cytokines and growth factors
2017 · Cochrane All outcomes
2017-05Not listedNot assessed
How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.