Nicotine EC vs behavioural support only/no support: Serious adverse events – measured by self‐report and medical records
It is very uncertain whether nicotine EC changes serious adverse events at 4 weeks to 8 months Assessed via… compared with behavioural support only/no support (very low certainty).
What each review found
Current versions only| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Nicotine EC vs behavioural support only/no support Serious adverse events at 4 weeks to 8 months Assessed via self‐report and medical records · People who smoke It is very uncertain whether nicotine EC changes serious adverse events at 4 weeks to 8 months Assessed via… compared with behavioural support only/no support (very low certainty). Electronic cigarettes for smoking cessation (2024) · Cochrane Headline outcomes only | RR 0.89 [0.59, 1.34] | 10 studies · 3263 participants | Very low |
Nicotine EC vs behavioural support only/no support Serious adverse events at 4 weeks to 8 months Assessed via self‐report and medical records · People who smoke It is very uncertain whether nicotine EC changes serious adverse events at 4 weeks to 8 months Assessed via… compared with behavioural support only/no support (very low certainty). Electronic cigarettes for smoking cessation (2022) · Cochrane Headline outcomes onlyearlier version CD010216.PUB7, superseded | RR 1.03 [0.54, 1.97] | 9 studies · 1993 participants | Very low |
Nicotine EC vs behavioral support only/no support Serious adverse events at 4 weeks to 6 months Assessed via self‐report and medical records · People who smoke It is very uncertain whether nicotine EC changes serious adverse events at 4 weeks to 6 months Assessed via… compared with behavioral support only/no support (very low certainty). Electronic cigarettes for smoking cessation (2021) · Cochrane Headline outcomes onlyearlier version CD010216.PUB5, superseded | RR 1.17 [0.33, 4.09] | 6 studies · 1011 participants | Very low |
Nicotine EC vs behavioural support only/no support Serious adverse events at 4 weeks to 6 months Assessed via self‐report and medical records · People who smoke It is very uncertain whether nicotine EC changes serious adverse events at 4 weeks to 6 months Assessed via… compared with behavioural support only/no support (very low certainty). Electronic cigarettes for smoking cessation (2021) · Cochrane Headline outcomes onlyearlier version CD010216.PUB6, superseded | RR 1.51 [0.7, 3.24] | 7 studies · 1303 participants | Very low |
Nicotine EC vs behavioural support only/no support Serious adverse events at 4 weeks to 6 months Assessed via self‐report and medical records · People who smoke It is very uncertain whether nicotine EC changes serious adverse events at 4 weeks to 6 months Assessed via… compared with behavioural support only/no support (very low certainty). Electronic cigarettes for smoking cessation (2020) · Cochrane Headline outcomes onlyearlier version CD010216.PUB4, superseded | RR 1.33 [0.25, 6.96] | 5 studies · 842 participants | Very low |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Electronic cigarettes for smoking cessation 2024 · Cochrane Headline outcomes only | Not reported | list not extracted yet | Not assessed |
Studies behind the findings
None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.