Question · asked by 1 review
Bethanechol vs Artificial saliva: Side effects
- Population
- Patients receiving radiotherapy on its own or in addition to chemotherapy to the head and neck region
- Intervention
- Bethanechol
- Comparison
- Artificial saliva
- Outcome
- Side effects
What each review found
Current versions only| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Bethanechol vs Artificial saliva Side effects · Patients receiving radiotherapy on its own or in addition to chemotherapy to the head and neck region Pharmacological interventions for preventing dry mouth and salivary gland dysfunction following radiotherapy (2017) · Cochrane All outcomes | Low rates of adverse effects (watering eyes, nervousness, frequent urination, sweating, warm face, cramps, diarrhoea, nausea) with insufficient evidence of any differences (Jham 2007) | 1 study | GRADE not reported |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Pharmacological interventions for preventing dry mouth and salivary gland dysfunction following radiotherapy 2017 · Cochrane All outcomes | 2016-09 | Not listed | Not assessed |
Related questions
The same intervention and outcome, asked in another population or against another comparator.
- Bethanechol vs placebo · Patients receiving radiotherapy on its own or in addition to chemotherapy to the head… · 1 review
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.