Question · asked by 1 review

5‐ASA vs placebo: Relapse, drop‐outs classed as relapse, grouped by length of

5‐ASA showed no clear difference in relapse, drop‐outs classed as relapse, grouped by length of compared with placebo (moderate certainty).

What each review found

Current versions only
FindingEffectStudiesGRADE certainty
5‐ASA vs placebo
Relapse, drop‐outs classed as relapse, grouped by length of · patients with maintenance of medically‐induced remission in Crohn's disease
5‐ASA showed no clear difference in relapse, drop‐outs classed as relapse, grouped by length of compared with placebo (moderate certainty).
Oral 5‐aminosalicylic acid for maintenance of medically‐induced remission in Crohn's disease (2016) · Cochrane Headline outcomes only
RR 0.98 [0.91, 1.07]11 studies · 2014 participantsModerate
5‐ASA vs placebo
Relapse, drop‐outs classed as relapse, grouped by length of · patients with maintenance of medically‐induced remission in Crohn's disease
5‐ASA showed no clear difference in relapse, drop‐outs classed as relapse, grouped by length of compared with placebo (low certainty).
Oral 5‐aminosalicylic acid for maintenance of medically‐induced remission in Crohn's disease (2016) · Cochrane Headline outcomes only
RR 0.99 [0.8, 1.23]1 study · 161 participantsLow
5‐ASA vs placebo
Relapse, drop‐outs classed as relapse, grouped by length of · patients with maintenance of medically‐induced remission in Crohn's disease
5‐ASA showed no clear difference in relapse, drop‐outs classed as relapse, grouped by length of compared with placebo (moderate certainty).
Oral 5‐aminosalicylic acid for maintenance of medically‐induced remission in Crohn's disease (2016) · Cochrane Headline outcomes only
RR 1.07 [0.86, 1.33]1 study · 132 participantsModerate

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Oral 5‐aminosalicylic acid for maintenance of medically‐induced remission in Crohn's disease
2016 · Cochrane Headline outcomes only
Not reportedlist not extracted yetNot assessed

Studies behind the findings

None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.