Question · asked by 1 review
Azoles vs terbinafine: Adverse events
- Population
- participants with confirmed toenail onychomycosis
- Intervention
- Azoles
- Comparison
- terbinafine
- Outcome
- Adverse events
Azole showed no clear difference in adverse events compared with terbinafine (moderate certainty).
What each review found
Current versions only| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Azole vs terbinafine Adverse events · participants with confirmed toenail onychomycosis Azole showed no clear difference in adverse events compared with terbinafine (moderate certainty). Oral antifungal medication for toenail onychomycosis (2017) · Cochrane Headline outcomes only | RR 1 [0.86, 1.17] | 9 studies · 1762 participants | Moderate |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Oral antifungal medication for toenail onychomycosis 2017 · Cochrane Headline outcomes only | Not reported | Not extracted | Not assessed |
Related questions
The same intervention and outcome, asked in another population or against another comparator.
- Azoles vs placebo · participants with confirmed toenail onychomycosis · 1 review
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.