Fluoride varnish vs No fluoride treatment: Dimensional change (size) of early enamel caries lesions
- Population
- Patients (mainly children) with white spot lesions (WSL)
- Intervention
- Fluoride varnish
- Comparison
- No fluoride treatment
- Outcome
- Dimensional change (size) of early enamel caries lesions
In one trial, professionally applied sodium fluoride varnish significantly reduced the size of early enamel caries lesions compared with no fluoride treatment; ungraded.
What each review found
Include earlier review versions| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Professionally applied sodium fluoride (NaF) varnish vs No fluoride treatment Dimensional change (size) of early enamel caries lesions · Children with white spot lesions / early enamel caries · Children in clinical dental settings In one trial, professionally applied sodium fluoride varnish significantly reduced the size of early enamel caries lesions compared with no fluoride treatment; ungraded. Caries remineralisation and arresting effect in children by professionally applied fluoride treatment - a… (2016) All outcomes | One clinical trial (Du 2012) evaluating dimensional change reported that the average size of early enamel caries in children receiving professional NaF therapy was significantly smaller than in those with no fluoride… | 1 study | GRADE not reported |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Caries remineralisation and arresting effect in children by professionally applied fluoride treatment - a systematic review. 2016 All outcomes | Publications from 1948 to 2014 (search date not reported) | 17 | Critically Low / Critically Low |
Studies behind the findings
The primary studies the full-text reviews tie to this outcome. Reviews with headline outcomes only do not list them here.
- Randomized controlled trial on fluoride varnish application for treatment of white spot lesion after fixed orthodontic treatment. · 2012 · included by 1 of these review
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.