Question · asked by 1 review

SDF (given at a particular frequency, concentration, or duration) vs SDF (given at a different frequency, concentration, or duration): Adverse effects

Population
Children and adults (with or without carious lesions)
Intervention
SDF (given at a particular frequency, concentration, or duration)
Comparison
SDF (given at a different frequency, concentration, or duration)
Outcome
Adverse effects

What each review found

Current versions only
FindingEffectStudiesGRADE certainty
SDF (given at a particular frequency, concentration, or duration) vs SDF (given at a different frequency, concentration, or duration)
Adverse effects · Children and adults (with or without carious lesions) · 24 to 30 months, Children
Topical silver diamine fluoride (SDF) for preventing and managing dental caries in children and adults (2024) · Cochrane All outcomes
1 study (203 children) reported that black or brown staining on treated lesions was commonly found in both groups, with little or no difference according to whether SDF treatment was given in 3 applications at…3 studies · 1121 participantsVery low

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Topical silver diamine fluoride (SDF) for preventing and managing dental caries in children and adults
2024 · Cochrane All outcomes
2023-06Not listedNot assessed
How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.