QUETIAPINE vs RISPERIDONE: Adverse effects: 2. Extrapyramidal effects ‐ use of antiparkinson medication
- Population
- schizophrenia
- Intervention
- QUETIAPINE
- Comparison
- RISPERIDONE
- Outcome
- Adverse effects: 2. Extrapyramidal effects ‐ use of antiparkinson medication
QUETIAPINE probably leads to lower adverse effects: 2. Extrapyramidal effects ‐ use of antiparkinson… compared with RISPERIDONE (moderate certainty).
What each review found
Current versions only| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
QUETIAPINE vs RISPERIDONE Adverse effects: 2. Extrapyramidal effects ‐ use of antiparkinson medication · participants with schizophrenia QUETIAPINE probably leads to lower adverse effects: 2. Extrapyramidal effects ‐ use of antiparkinson… compared with RISPERIDONE (moderate certainty). Quetiapine versus other atypical antipsychotics for schizophrenia (2013) · Cochrane Headline outcomes only | RR 0.5 [0.36, 0.69] | 8 studies · 2163 participants | Moderate |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Quetiapine versus other atypical antipsychotics for schizophrenia 2013 · Cochrane Headline outcomes only | Not reported | Not extracted | Not assessed |
Related questions
The same intervention and outcome, asked in another population or against another comparator.
- QUETIAPINE vs PALIPERIDONE · schizophrenia · 1 review
- QUETIAPINE vs ZIPRASIDONE · schizophrenia · 1 review
- QUETIAPINE vs ARIPIPRAZOLE · schizophrenia · 1 review
- QUETIAPINE vs CLOZAPINE ‐ all data short term · schizophrenia · 1 review
- QUETIAPINE vs OLANZAPINE · schizophrenia · 1 review
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.