Homocysteine‐lowering interventions (Folic Acid, Vitamin B6 and Vitamin B12) vs placebo or usual care: Stroke
Homocysteine‐lowering interventions (Folic Acid, Vitamin B6 and… showed no clear difference in stroke compared with placebo or standard care (high certainty).
What each review found
Current versions only| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Homocysteine‐lowering interventions (Folic Acid, Vitamin B6 and Vitamin B12) vs placebo or standard care Stroke · patients with preventing cardiovascular events Homocysteine‐lowering interventions (Folic Acid, Vitamin B6 and… showed no clear difference in stroke compared with placebo or standard care (high certainty). Homocysteine‐lowering interventions for preventing cardiovascular events (2013) · Cochrane Headline outcomes onlyearlier version CD006612.PUB3, superseded | RR 0.91 [0.82, 1.01] | 8 studies · 40815 participants | High |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Homocysteine‐lowering interventions for preventing cardiovascular events 2017 · Cochrane Headline outcomes only | Not reported | list not extracted yet | Not assessed |
Studies behind the findings
None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.