Question · asked by 1 review
RISPERIDONE vs placebo: Adverse events including extrapyramidal effects
- Population
- terminally ill adults with delirium
- Intervention
- RISPERIDONE
- Comparison
- placebo
- Outcome
- Adverse events including extrapyramidal effects
Summary of findings: risperidone showed no clear difference in adverse events including extrapyramidal effectsd compared with placebo (low certainty).
What each review found
Current versions only| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Summary of findings: risperidone vs placebo Adverse events including extrapyramidal effectsd · terminally ill adults with delirium Summary of findings: risperidone showed no clear difference in adverse events including extrapyramidal effectsd compared with placebo (low certainty). Drug therapy for delirium in terminally ill adults (2020) · Cochrane Headline outcomes only | MD 0.73 | 1 study · 111 participants | Low |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Drug therapy for delirium in terminally ill adults 2020 · Cochrane Headline outcomes only | Not reported | Not extracted | Not assessed |
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.