Question · asked by 1 review

Treatment of eclampsia: loading dose alone vs loading dose + maintenance regimen: Maternal death

Population
women with eclampsia
Intervention
Treatment of eclampsia: loading dose alone
Comparison
loading dose + maintenance regimen
Outcome
Maternal death

It is very uncertain whether treatment of eclampsia: loading dose alone changes maternal death compared with loading dose plus maintenance dose regimen (very low certainty).

What each review found

Current versions only
FindingEffectStudiesGRADE certainty
Treatment of eclampsia: loading dose alone vs loading dose plus maintenance dose regimen
Maternal death · women with eclampsia
It is very uncertain whether treatment of eclampsia: loading dose alone changes maternal death compared with loading dose plus maintenance dose regimen (very low certainty).
Alternative magnesium sulphate regimens for women with pre‐eclampsia and eclampsia (2023) · Cochrane Headline outcomes only
RR 2.59 [0.11, 61.75]1 study · 80 participantsVery low

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Alternative magnesium sulphate regimens for women with pre‐eclampsia and eclampsia
2023 · Cochrane Headline outcomes only
Not reportedNot extractedNot assessed
How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.